Preptin hormone level and some biochemical parameters in type 2 diabetic patients in Samarra city




Preptin hormone, Diabetes, Na, K, GSH, and MDA.


The study included evaluation of preptin level and  some biochemical parameters in sera of type 2 diabetes patients. The study included (60) samples of type 2 diabetes patients with age ranged between (45-73) years old, as well as (40) of blood samples of apperently healthy individuals as control with ages ranged between (40-70) years old. The results showed a significant increase at (p ≤0.05) in perpetin level of patients (263.43±178.31 ng/ml) compared with control (86.46 ±15.87 ng/ml). Glucose level showed a significant increase at (p ≤0.05) in patients group (245.7 ± 43.5mg/dL) compared with control (89.9 ± 9.7 mg/dL). The results also indicates a significant increase at (p ≤0.05) in sodium and potassium ions levels (161.431± 34.168 and 5.77± 1.90 mmol/L) respectively in patients compared with control (145.241± 19.85 and 3.86± 0.68 mmol/L) respectively. The level of glutathione decreased  at (p ≤0.05) significantly in sera of diabetes patients (0.192± 0.070 μmol/l) compared with control (0.379± 0.147μmol/l), while malon dialdehyde level was increased significantly (5.110± 2.833μmol/l) in patients compared with control (1.115 ± 0.762 μmol/l(