The relationship between Interleukin-22 concentration and some types of bacteria that were isolated from wounds and surgical operations in Samarra city/ Iraq
Keywords:Interleukin-22, wound, bacteria, Staph.aureus, Pseudomonas
The current study was conducted to estimate the level of the interleukin 22 concentration level and its relationship with some bacterial species in people who had wounds and surgeries. The study included 40 samples of swabs and blood samples from patients with wound infections who attended Samarra General Hospital and some outpatient clinics, and their ages ranged between (12-68) years and of both sexes, for the period from November 2021 to the end of March 2022. The information was recorded in a questionnaire for information about the person within the subject of the study. The samples were divided into wound infection samples for 30 surgical patients and control samples for the healthy 10 samples. The results of the current study showed a significant decrease of P≤0.01 in the level of interleukin IL-22 concentration in patients who underwent surgical operations (13 pg/ml) compared to its level in control groups (37.13 pg/ml). The level of the concentration of the interleukin IL-22 decreased in the subjects with bacterial growth (Staph.aureus, Pseudomonas, Proteus, Klebsiella, E. coli) (14.66, 9.92, 17.08, 11.73, 11.67 pg/ml), respectively, and differently among people who had wounds and surgeries, as the results showed that the level of IL-22 concentration decreased by different levels. Heterogeneous to those infected and according to the type of bacterial growth that appeared in them.
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