Effect of aqueous extract of strawberry fruit on some enzymatic changes of liver and heart in male white rabbits subject to Oxidative stress induced with paracetamol

Abstract

The current study aimed to test the hepatic effect of strawberry fruits in male rabbits treated with paracetamol and to try to determine the mechanisms of this action on liver enzymes and some other factors under study. According to the findings, ceruloplasmin levels in blood serum significantly decreased as oxidative stress caused by paracetamol developed in the white male rabbit. The findings also showed a significant (P≤0.05) increase in phospholipids in the serum of acetaminophen-treated rabbits when compared to the healthy control group, as well as a significant rise in serum CK enzyme activity, alanine aminotransferase enzyme activity, and a significant rise in aspartate aminotransferase AST enzyme activity. And Significant variations (P0.05) in the activity of alkaline phosphatase (ALP) in the blood serum of the rabbits treated with paracetamol compared to the healthy control group, together with a significant rise (P0.05) in the gamma-glutamyltransferase enzyme activity.