Studying the Risk Factors on COVID-19 Patients in Nineveh Governorate

Abstract

The world witnessed a major crisis when the new Corona virus (Covid-19) appeared, and its effects are still continuing, as no gender, race, age, or color was excluded from infection, and given the disease represented by a pandemic that spread in most parts of the world in recent years and still poses a threat to Therefore, it is a fertile field for studies and to delve into it extensively. This research included a study of the effect of infection times, obesity, smoking and age on the levels of enzymes: lactoperoxidase (LP), lactate dehydrogenase (LDH), alanine aminotransferase (ALT), and aspartate aminotransferase (AST), as well as measuring interleukin-6 (IL-6). In Nineveh Governorate, (100) samples were collected from Covid patients (50) and a healthy group (50), whose ages ranged between (20-70) years and for both sexes. It was observed that there was a high significant increase (0.0001) in all the measured enzymes (LP, LDH, ALT and AST) as well as an increase in the level of IL-6 when comparing the total COVID-19 patients with the control group. The results showed that there was a significant increase in the levels of different enzymes (LP, LDH, ALT and AST), as well as IL-6 level in patients with COVID-19 aged 40 years and over, compared with the group of patients aged (20-39) years, as well as among patients who smoked compared to with non-smokers and control group. The results showed that there was a high significant increase in all variables measured in patients with obesity, more than patients with normal weights and control group. In addition, it was observed that there was a high significant increase in activity of LP when the number of infections increased in patients with Covid-19, and an increase in the activity of LDH, ALT and AST and the level of IL-6 in patients with Covid infected once compared with patients infected more than once and when compared with control group. The study concluded that there are clear effects of the levels of measured enzymes (LP, LDH, ALT, AST) and level of IL-6 in patients with COVID-19, and the factors of age, smoking, obesity, and the incidence of infection for one time had the greatest effect on the level of the measured variables, which reflect the increase in the severity of the disease in infected patients.