Measuring the level of some immunological indicators in patients with hypersensitivity type 1

Abstract

Forty-two samples were collected from people suspected of having hypersensitivity type 1, males and females, of different ages. The results showed that 22 of the infected samples were a result of urticaria and 10 allergens of a food source, and 10 samples from people who did not show any allergic condition and considered a control sample. The results showed that the concentration of IgE antibody was 10.1 ng/ml for urticaria samples and 9.0 ng/ml for food allergy, compared to 5.6 ng/ml for healthy subjects, while the level of IgG in each of the urticaria and food allergy samples was 30.1 and 27.3, respectively, with a significant difference from the control. As for IgM, although there was a significant difference between the patients and the healthy sample, it was within the normal limits. The results showed that subjects with urticaria and food allergy had an increased concentration of IL-4 and IL-5 compared to the control. The results of the complete blood count showed a significant increase in the white blood cells, Eosinphile. In addition to many differences in blood parameters compared to normal proportions. Some interleukins were also measured in the study sample, and it was found that the concentration of IL-4 and IL-5 increased compared to the standard sample, and there were no significant differences in the concentrations according to age groups. It was also found that the IgE concentration decreased with age, while the IgG antibody concentration increased compared to the standard sample and with the increase in age groups.