Evaluation Left Ventricle Performance in hypertensive patients using heart ultrasound and levels of a salt-producing brain peptide in blood


  • Hiba Hazim Tikrit university/ college of pharmacy




left ventricular (LV), speckle-tracking echocardiography (STE), B-type natriuretic peptide (BNP) and global longitudinal strain (GLS)


Background: we studied on 100 patients in total, with 56 in the 'LV dysfunction' group and the rest in the 'control' group to evaluate of left ventricular functioning in hypertensive patients by examining the ultrasound of the heart by tracking the scores and their association with levels of a salt-producing brain peptide in the blood. . To find relevant research, a thorough online search was conducted. Data were retrieved and synthesized from the included studies after they were evaluated for quality and risk of bias. The findings demonstrated a robust association between B-type natriuretic peptide (BNP) levels and speckle-tracking echocardiography (STE) derived indices of left ventricular (LV) performance in hypertension individuals. The findings of this review highlight the potential of STE as a valuable tool for evaluating LV performance in hypertensive patients and its association with BNP levels in Baghdad. Aim: This study aims to find out how hypertension patients' LV function, as determined by speckle-tracking echocardiography (STE), correlated with B-type natriuretic peptide BNP levels in the blood. Methods: All subjects had echocardiographic tests using a commercially available ultrasonography equipment equipped with a phased-array transducer operating at 3.5 MHz, with the following parameters measured: Biplane with a few tweaks for this study, the LVEF was calculated using Simpson's method ,the left ventricular systolic volume (SV) ,systolic volume at the end of the left ventricle (LVESV), in order to determine the LVMI, the Devereux formula was used and the filling ratio of early to late diastole (E/A ratio). They were compared with a healthy group (control) to obtain accurate results. Results: There were statistically significant differences in LVEF, LVEDV, LVESV, LVMI, E/A ratio, E/e' ratio, and global longitudinal strain (GLS) between the control and LV dysfunction groups. Diastolic dysfunction was more common in LV dysfunction patients, and they also had lower GLS values than the control group. The levels of BNP were shown to have a favorable relationship with numerous echocardiographic parameters. Hypertensive individuals had greater BNP levels than the control group. The LVH group also had greater levels of BNP than the non-LVH group.




How to Cite

Hazim, H. (2024). Evaluation Left Ventricle Performance in hypertensive patients using heart ultrasound and levels of a salt-producing brain peptide in blood. Samarra Journal of Pure and Applied Science, 6(2), 124–136. https://doi.org/10.54153/sjpas.2024.v6i2.686