Comparison study of some physiology and immunological parameter in hypertension patients

Abstract

High blood pressure is the most common chronic condition associated with a persistent increase in systolic blood pressure above 140 mm Hg and/or diastolic blood pressure above 90 mm Hg. This study aims to compare patients with recently diagnosed high blood pressure to healthy, disease-free individuals to ascertain the impact of the hormone irisin and the immunological response in these individuals This study was conducted on two groups: the first group consisted of 50 males and female patients suffering from high blood pressure as a primary pathology, and the second group consisted of 40 male and female control group, and their ages were between (20-50) years. The level of interleukins and the physiological hormone irisin were measured using ELISA device technology. The results of the study showed that there was a significant increase with statistical evidence (P ≥ 0.01) in the level of interleukin (IL-2, IL-1β, and IL-17) and the hormone irisin compared to the control group. It was concluded that there was a direct relationship between the level of the hormone Irisin in high blood pressure patients compared to healthy people. Also, there was a direct relationship between immune variables and high blood pressure patients compared to healthy people.