Measurement of thyroid gland function and some biochemical parameters in domestic male rabbits in which hyperprolactinemia is experimentally induced

Authors

  • Omar Abdullah Ahmed Department of Biotechnology, College of Applied Science, University of Samarra

DOI:

https://doi.org/10.54153/sjpas.2022.v4i1.338

Keywords:

Prolactin, Thyroid gland , Domperidone

Abstract

 

 

The current study aimed to identify the protective effect of walnut oil and Indian premium oil and compare their effect with the effect of L-Carnitin on some physiological and biochemical parameters of local male rabbits suffering from experimentally induced hyperprolactinemia. T4. Hyperprolactinemia was induced in male rabbits used in the study by subcutaneous injection of domperidone at a concentration (4 mg/kg) dissolved in physiological solution (normal saline) and Tween-80, simultaneously dosed at 0.5 ml/kg of walnut oil and walnut oil. The Indian premium and L-carnitine, each according to the specific group, for the purpose of identifying the preventive effect of each compound, and the duration of the experiment lasted (30 days). Rabbits were divided into 5 groups, the negative control group (the healthy control) (C-ve), the positive control group (the infected control) (C+ve) injected with domperidone, the Indian premium oil group (G1), the walnut oil group (G2) and the drug L-group. Carnitine (G3), and the following results were obtained for a significant (P≤0.05) increase in the concentration of T3 in the blood sera of local male rabbits in group (C+ve) compared to the rest of the groups. T4 showed an increase in carnitine group (G3) compared to the other of the groups, while TSH showed a significant increase in the (C+ve) and (C-ve) group compared to the other of the groups. And a significant increase (P≤0.05) in the concentration of albumin in the blood sera of local male rabbits in the positive control group (C+ve) and (G1) compared to the rest of the groups, while the total protein showed a significant increase in (G2) compared to the other of the groups.

Published

2022-03-31