Effect of oil extracted from rosemary and flaxseeds on oxidation factors and lipoproteins in male rabbits with Alzheimer's disease

Abstract

Alzheimer's disease is a neurodegenerative disease, many environmental and genetic factors contributed to the development of this disease. The underlying cause of the disease is a defect in amyloid plaques, neurofibrillary tangles, and loss of neural connections in the brain.                           Both rosemary and flax seeds were used as oil extracts, and the study included the use of two control groups of rabbits, as the healthy group included 5 rabbits and the group with Alzheimer’s disease 30 rabbits. As for malondaldehyde, its level increased, and the best treatment that significantly reduced its level was flaxseed oil. As for lipoproteins, it was found that the level of cholesterol increased in the affected group, and that the best treatment that worked to reduce its level was rosemary oil and flaxseed oil. As for the level of triglycerides, we note that its level increased in the affected group, and that the best treatment that worked to reduce its level after treatment was the drug and flaxseed oil. And the level of high-density proteins decreased in the affected group in the case of using rosemary oil as a treatment, as well as the drug with rosemary oil. In the case of low-density proteins, we notice that it increased in the affected group, and when using rosemary oil as a treatment and flaxseed oil. And very low-density proteins, we notice that when using rosemary oil, drug and rosemary oil, we notice that they significantly reduced its level, which was high in it.