Synthesis of Pyrazoles and Pyrazolones Moiety from diazonium salt of 1,3,4-thiadiazole

Authors

  • Ayad Abdullah Abdulrahman Department of Chemistry, College of Education for Pure Science, University of Mosul https://orcid.org/0009-0001-3501-7385
  • Jasim Ali Abdullah Department of Chemistry, College of Education for Pure Science, University of Mosul, Mosul

DOI:

https://doi.org/10.54153/sjpas.2024.v6i1.587

Keywords:

cyclic addition reactions, pyrazolone, diazonium salt and thiadiazole

Abstract

The diazonium salt of [2,2'-bi(1,3,4-thiadiazole)]-5,5'-diamine (BTD) and 5-(1-phenylprop-1-en-2-yl)-1,3,4-thiadiazol-2-amine (PTA) was coupled with ethyl acetoacetate, ethyl benzoylacetate and benzylacetone to give the corresponding diazo compounds under basic media. These products were allowed to react with hydrazine hydrate and phenylhydrazine under conventional method to give pyrazole and pyrazolone derivatives in high yields.

Published

2024-06-30

How to Cite

Abdullah Abdulrahman, A., & Ali Abdullah, J. (2024). Synthesis of Pyrazoles and Pyrazolones Moiety from diazonium salt of 1,3,4-thiadiazole. Samarra Journal of Pure and Applied Science, 6(2), 33–46. https://doi.org/10.54153/sjpas.2024.v6i1.587