Estimating the concentration of apolipoprotein B and some biochemical indicators and its relationship to high blood pressure in patients in the city of Samarra

Abstract

Summary

Hypertension is a silent killer that increases disease infection and death rates, It is one of the most common diseases that greatly affect the heart, blood vessels, brain and kidneys. It is associated with high fat profile and is considered one of the most common risk factors for hypertension. The study included (89) samples with (57) samples affected by hypertension disease consisting of (27) female and (30) male, and (32) control samples consisting of (13) females and (19) males whose ages ranged between (30-85) years. The results of measuring the concentration of Cholesterol(Chol), Triglycerides (TG), High-density lipoproteins (HDL) , Very low-density lipoproteins (VLDL), and Apolipoprotein B (APOB), in patients with hypertension compared to healthy ones, have a significant increase in the level of the cholesterol concentration in patients with hypertension, which amounted to 187.3 mg / dl compared to healthy ones , which amounts to 158.8 mg / dl. As for triglycerides, their concentration in patients reached 177.3 mg / dl compared to healthy ones , which amounts to 144.2 mg / dl. While the results of lipoproteins shows a significant decrease in the level of HDL concentration in patients with hypertension, which reached 37.42 mg / dl , compared to healthy ones, it was 46.10 mg / dl. Both LDL and VLDL levels had significantly higher levels of concentration among patients, reaching 113.4 and 34.36 mg / dl, respectively, in comparison with their concentration in healthy ones, they reaches 81.2 and 29.33 mg / dl, respectively. Significant increase is recorded in the level of Apolipoprotein B concentration in patients with hypertension as it reached 2017 ng / ml. in comparison of healthy ones with a concentration of 1830 mg / ml While the results showed that the blood glucose concentration did not record significant differences between the sera of patients who reached 94.4 ± 23.5 mg / dl while (88.7 ± 22.1) mg / dl was in healthy blood sera as a control group.