Evaluation of hepcidin and iron levels in patients with kidney failure
DOI:
https://doi.org/10.54153/sjpas.2024.v6i4.855Keywords:
Renal Failure ,Hepcidin , Iron, Urea ,Creatinine.Abstract
The current study aimed to measure the concentration of iron and the hormone hepcidin in patients with kidney failure. Study samples were collected from private clinics in Samarra and from Al-Karama Teaching Hospital (dialysis center) in Baghdad. The samples were divided into three groups before dialysis. And the group after washing, in addition to the control group, (105) blood samples were collected, distributed as follows: (40) blood samples before washing and (40) blood samples after washing, in addition to the control group consisting of (25) blood samples ranging in age from individuals. The three samples were between (25-65) years old, all of them male. The ages of the patients ranged between (30-65) years, and the ages of the control group were between (25-50) years. The results of the study showed that there were significant differences (P≤0.05) in the effectiveness of The hormone hepcidin, as it was observed that there was a significant decrease in its level in patients with kidney failure before dialysis by (8.16±2.41) ng/ml, and after dialysis by (8.02±2.01) ng/ml, compared with the control group (16.69±5.42) ng/ml , while the results of the statistical analysis did not show any significant differences in the average values of iron for patients with kidney failure before dialysis (86.1±18.7)Mcg/dl, and after dialysis (90.32±17.56)Mcg/dl compared with the control group (93.16±22.5) mcg/dl.
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