Evaluation of the effect of Cordia myxa Probiotic against bacteria isolated from respiratory tract Patients

Abstract

Collected 120 samples of Sptum and upper pharyngeal swabs from patients with respiratory infections, from Samarra General Hospital and some outpatient clinics for ages (15_55) years. from October 2023 until the end of February 2024. The isolated bacteria were diagnosed as K.pneumonia, except for the percentage among the isolated bacterial species and a percentage of 30%, followed by P.aeruginasa isolates with rate of 22%. Small analyses of antibiotics Azithromycin (AZM), Ciprofloxacin (CIP), Amoxcillin and Clavulanic acid (AMC) and Cefataxim (CTM) are also being tested. The results showed that K. pneumonia were resistance to all antibiotics used, and the highest resistance rate was to Amoxcillin, Clavunic acid, and Cefataxim, reaching 100% and 94.4% respectively. The extraction rate was 21.7% for the alcoholic extract, Different test solutions were used to detect secondary metabolites, which revealed the presence of flavonoids, phenols, tannins, glycosides and saponins in both aqueous and alcoholic extracts of the cordia myxa. The pathogenic bacteria which isolate in this study appears inhibitory zone diameters for the alcoholic extract of the cordia myxa fruits of 20 mm and 22 mm for the K. penumonia and P. aeruginsa respectively. the sensitivity of the bacteria towards the alcoholic extract increased in a direct relationship with the cordia myxa extract fermented with L. Plantrium probiotics to 32 mm against P. aeruginasa.