Evaluation of the effectiveness of the enzyme monoamine oxidase with some biochemical variants in patients with atherosclerosis

Authors

  • Saad Kassim Mohammed Jaber Department of Chemistry, College of Science, Tikrit University, Iraq
  • Ibrahim Fahd Wahid Department of Chemistry, College of Science, Tikrit University, Iraq
  • Othman Rashid Al Samarrai Department of Chemistry, College of Education, University of Samarra, Iraq

DOI:

https://doi.org/10.54153/sjpas.2024.v6i3.605

Keywords:

monoamine oxidase enzyme, glutathione, malondialdehyde, lipids, atherosclerosis.

Abstract

Abstract

Atherosclerosis is one of the heart diseases that are widespread all over the world and are associated with many chronic diseases, so this study aimed to evaluate the effectiveness of the enzyme monoamine oxidase with some biochemical variables in patients with atherosclerosis. The study included 100 blood serum samples, 50 of them for patients with atherosclerosis aged 35-70 years, collected from Salah al-Din General Hospital, and 50 samples for healthy people as a control group and the same age group. The results of the study showed a significant increase in the effectiveness of the enzyme monoamine oxidase at the level of probability (P≤ 0.05) in the blood of patients with atherosclerosis compared with the healthy group, the effectiveness of the enzyme reached 38.590 ± 301.515 micromol/l/min compared with healthy, which amounted to 9.887±94.107 micromol/l/min. The results also showed a significant increase in the levels of cholesterol, triglycerides, low-density lipoproteins-cholesterol and very low-density lipoproteins-cholesterol, as well as a significant increase in Malon-aldehyde and nitric oxide and a significant decrease in clotathione in the patient group compared with the healthy group of Evaluation of the effectiveness of monoamine oxidase enzyme with some biochemical variables in patients with atherosclerosis.

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Published

2024-09-30

How to Cite

Mohammed Jaber, S. K., Fahd Wahid, I., & Rashid Al Samarrai, O. (2024). Evaluation of the effectiveness of the enzyme monoamine oxidase with some biochemical variants in patients with atherosclerosis. Samarra Journal of Pure and Applied Science, 6(3), 14–22. https://doi.org/10.54153/sjpas.2024.v6i3.605

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