Cloud Point Extraction Coupled with UV-Vis Spectrophotometry for Micro Determination of Amlodipine in Pharmaceuticals

Authors

  • Adnan Majeed Alsamarraie Department of Applied chemistry,college of Applied science,University of Samarra,
  • Imad Tarek Hanoon Department of Chemistry, College of Education, University of Samarra, Iraq

DOI:

https://doi.org/10.54153/sjpas.2024.v6i3.691

Keywords:

Amlodipine, Cloud Point, Micelles

Abstract

The main objective of proposed method, cloud point extraction method (CPE) is to estimate the concentrations of Amlodipine, in pure and pharmaceutical forms, by adding 2 ml of 5 μg/ml of metanil yellow for Amlodipine, adding 1.5 ml of 10%v/v Triton X-114 with 1.5 ml of 0.1M of CTAB, and added 2ml of sodium sulphate solution 5%. The acidic function at pH = 6 is then placed in the ultrasound for five minutes. The bathroom is then transported for 40 minutes and 50°C. It is then, placed in a test tube in the centrifuge for 10 minutes and 5000 rpm. Then, transported to an ice bath and for two minutes, Absorbance measured at 664nm, A sign of Sandle were 0.003619 µg/cm2, LOD was 0.0471 µg.ml-1 and LOQ was 0.1428 µg.ml-1.

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Published

2024-09-30

How to Cite

Alsamarraie, A. M., & Imad Tarek Hanoon. (2024). Cloud Point Extraction Coupled with UV-Vis Spectrophotometry for Micro Determination of Amlodipine in Pharmaceuticals. Samarra Journal of Pure and Applied Science, 6(3), 72–82. https://doi.org/10.54153/sjpas.2024.v6i3.691

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