Investigating fungi associated with human corneal infections among patients in Ramadi

Abstract

Fungal keratitis is a major contributor to ocular morbidity. The gradual progression, overlapping characteristics, diagnostic complexity, and potential consequences of fungal keratitis present a significant clinical problem. The rising trend can be related to the utilization of contact lenses, non-judicial corticosteroids, and vegetative trauma. Prompt identification and treatment are essential for effectively managing it. Understanding the pathological progression and clinical features of fungal keratitis is crucial for promptly diagnosing and treating the condition, leading to a decrease in ocular complications.  A total of 50 specimens from infected eyes were collected and studied microbiological 30 Positive fungal growth was selected during September to November   2023 from patients admitted in different hospitals in Ramadi city patients and private clinical were subjected to direct examination by 10% KOH mount, gram stain and culture PDA, SDA. Eye infections in relation to sex revealed that female cases 18(62.07%) were higher than those of males 11(37.93%). Infection in relation to age group indicated that those of age more than 40 years 14(48.28 %) were the most susceptible. Also, infections in relation to geographical area of patients revealed that, the rural 15 (55.56 %) were higher than Patients living in a city 12(44.44 %). Distribution of isolates fungal eye infections according to growth rate a total of 30 Positive fungal growth, species related to type of fungus were identified of which Asporgillus nigar 20 (66.67%) were the most prevalent, while Fusarium oxysporum recorded 7 (23.33 %), the lowest percentage recorded Fusarium solani 3 (10 %). Mycotic keratitis is a severe issue that typically occurs after an injury to the cornea. It necessitates prompt diagnosis and identification of fungal agents in order to administer appropriate therapy and avoid catastrophic outcomes. The species Asporgillus nigar was the most common fungal isolate.