Assessment of Spexin and Oxidative Stress Biomarkers in Acute Myocardial Infarction Patients
DOI:
https://doi.org/10.54153/sjpas.2026.v8i2.1236Keywords:
Myocardial Infarction, hormone spexin, superoxide dismutase, glutathione, and MalondialdehydeAbstract
The current study included collecting 90 blood samples from Ibn Al-Bitar Center for Cardiac Surgery in Baghdad for the period from 1/25/2024 to 3/15/2024, 60 samples from patients with Myocardial Infarction. All newly diagnosed patients were males and 30 healthy controls, all males, were used as a control group with ages ranging from 30 to 65 years. The study included: Estimation of the level of spexin hormone, activity of superoxide dismutase and level glutathione and Malondialdehyde. The results of the current study showed a significant decrease at the probability level (p≤0.05) Levels of spexin, activity superoxide dismutase, and glutathione in the sera of patients with myocardial infarction compared with the control group. A significant increase in the serum level of Malondialdehyde in the myocardial infarction patient group compared to the control group. The correlation study showed that there are non-significant positive correlations between the hormone spexin and the enzyme superoxide dismutase (+) and the level of glutathione. However, there is a positive correlation between the hormone spexin and the (+) Malondialdehyde level.
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