Effect of the chemical preservative Propyl 4-hydroxybenzoate on liver tissue in male albino rats

Authors

  • Wurood Mohamed Mutar Department of Biology, College of Education, University of Samarra
  • Muneef Saab Ahmed Department of Biology, College of Education for Pure Sciences, University of Tikrit
  • Ayad Hameed Ibrahim Department of Anatomy and Histology, College of Veterinary Medicine, University of Tikrit

Keywords:

Preservatives, Propyl 4-hydroxybenzoate, Endocrine disruptors, Parabens

Abstract

The use of preservatives in the field of food allows the provision of types of food products and foods in the off-season,ةIt also allows pharmaceutical and cosmetic products to be used for long periods without being damaged by the growth of microorganisms. But recently, several disadvantages of these compounds have emerged, including parabens, which include Propyl 4-hydroxybenzoate, due to their frequent use due to their availability in large quantities, cheap prices, and easy access. Several concentrations (800, 400, 200) mg/kg/day were used in this study for 30 days. as these concentrations affected the liver tissue of adult white male rats. The concentration of 800 mg/kg had the greatest effect on it, as it led to hepatocyte hypertrophy and degeneration, and cellular infiltration. Lymphocytic, hemosiderin, and Kupffer cell hyperplasia.

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Published

2022-12-30

How to Cite

Mutar, W. M. ., Ahmed , M. S. ., & Ibrahim, A. H. . (2022). Effect of the chemical preservative Propyl 4-hydroxybenzoate on liver tissue in male albino rats. Samarra Journal of Pure and Applied Science, 4(4), 38–47. Retrieved from https://sjpas.com/index.php/sjpas/article/view/389

Issue

Vol. 4 No. 4 (2022): Samarra Journal of Pure and Applied Science

Section

Biology

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