Evaluate the Efficiency of Copper Nanoparticles and Compare them with a Group of Antibiotics Against Escherichia Coli Bacteria Isolated from Urinary Tract Patients
DOI:
https://doi.org/10.54153/sjpas.2025.v7i1.920Keywords:
Antibiotics ، Copper nanoparticles ، Urinary tract infection ، Escherichia coliAbstract
This study aims to assess the inhibitory effectiveness of copper nanoparticles against 47 diagnosed isolations belonging to Escherichia coli bacteria out of 100 isolated from Urinary tract patients and then compare them with 12 types of antibiotics. This study was conducted in the postgraduate laboratory of the Department of Life Sciences Faculty of Education of Samarra University from 3/9/2023 to 20/3/2024. The statistical analysis showed moral differences in the inhibitory diameters of nanoscale copper particles compared to antibiotics towards E.coli bacteria. Among the highest antibiotics that gave high inhibition are antibiotic antibiotics 40.3 40.1, 40.1, 40, 34.6, 38.5 at concentrations 0.2, 0.1, 0.075, 0.050, 0.025 mg/ml, respectively, followed by anti-Cefotaxime giving high effectiveness with inhibition diameters 40.3, 40.1, 39.7 38.2, 34.1, mm, followed by counter 40.4 Ceftriaxone 40.3, 34.5, 32.2, 30.0 mm, followed by antibiotic Tetracycline gave drops inhibited 40.3, 40.1, 40, 38.4 30.1, mm, as for anti-Gentamicin it was inhibitive diameters 40.1, 37.4, 40.1, 34.8 33.2, mm, the anti-Samacycline has given drops inhibited, 39.4 38.0, 34.7, 32.5 30.1, mm, while Nitrofurantoin has given inhibition drops 35.1, 34,33.4, 32.4, 30.0 mm, as for the anti-Ciprofloxacin it gave the diameters inhibited 40.1 38.2, 25.7, 31.0, 23.5 mm, the anti-Azithromycin it gave the drops inhibited, 31.5 29.4, 30, 28.0, 25.6 mm, the anti-Sulfamethoxazole has given drops inhibited by 10.1,13.1 17.7, 14.7, 13.1, mm. Amoxicillin gave inhibition droplets, 28, 22.8 12.1, 14.5,14.5mm. The anti-Ampicillin gave diameters inhibited by 16.7 13.1,, 16.4 and 13.0, 10.1 mm. The inhibitory effectiveness results of CuONPs against E.coli bacteria as the inhibitory effectiveness diameter rates varied, as the inhibitory diameters were 30.1 28.1, 26.1, 25.2, 33.2, mm respectively at 0.2, 0.1, 0.075, 0.050, 0.025 mg/mL. These results of the possession of nanoparticles have shown high inhibitory effectiveness against bacteria.
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