Effect of some plant extracts (Syzygium aromaticum and Anthemis nobilis) against Streptococcus pyogenes

Abstract

Streptococcal diseases are associated with respiratory tract infection that is a substantial reason of morbidity and mortality through the world. Plant extracts and other biological active compounds isolated from plants have increased wide spread interest for the treatment of disease since ancient time. This research amid to estimate the inhibitory activity of alcoholic extracts of Syzygium aromaticum and Anthemis nobilis against eight isolates of pathogenic bacteria Streptococcus pyogenes obtained from patients with respiratory tract infections who visiting Tikrit Teaching Hospital, and compare this antimicrobial activity with the activity of some antibiotic to inhibit bacterial growth using susceptibility test antibiotic. Antimicrobial activity was measured by using disc diffusion method. Result revealed that the all isolates more sensitive to alcoholic extract of Syzygium aromaticum at the concentration 100% and less sensitive to other concentrations, while the extract of Anthemis nobilis had no inhibition effect against all strains of S. pyogenes. Results of susceptibility test antibiotic revealed that all bacteria isolates were sensitive toCirpfloxacin, Amikacin, Gentamicin 100%, while all the isolates were resistant to other antibiotic at different rates (Trimethoprim/sulphamethoxazole 87.5%, Piperacillin 50%, Amoxicillin 75%, Meropenem 25%, and Ceftriaxone 12.5%). From these results we concluded that the inhibitory activity of alcoholic clove extract at 100% and 75% was comparable to that of to Cirpfloxacin, Amikacin, Gentamicin antibodies on the growth of these bacterial isolates.