المعزولة من مرضى المسالك البولية Esherichia coli تقييم كفاءة جسيمات النحاس النانوية ومقارنتها مع مجموعة من المضادات الحيوية ضد بكتريا
DOI:
https://doi.org/10.54153/sjpas.2025.v7i1.920الكلمات المفتاحية:
Antibiotics ، Copper nanoparticles ، Urinary tract infection ، Escherichia coliالملخص
اجريت هذه الدراسة من اجل تقيم كفاءة جسيمات النحاس النانوية ومقارنتهامع12المضادات الحيوية التالية Gentamicin (GN),Ciprofloxacin (CIP), Azithromycin (AZM), Penicillin (PEN), Amoxicillin(AMX), Co-Amoxiclav(CA), Sulfamethoxazole (SUL), Nitrofurantoin) (NIT), Samacycline (SAM), Tetracycline (TET), Ceftriaxone(CTR), Cefotaxime( CTX).ضد بكتيريا Escherichia coli المعزولة من المسالك البولية واجريت الدراسة في قسم علوم الحياة كلية التربية جامعة سامراء في الفترة الممتدة من 5/9/2023 لغاية 1/1/2024 واظهرت النتائج فروق معنوية لجسمات النحاس النانوية مقارنة بالمضادات الحيوية في الدراسة على بكتريا Escherichia coli واظهرت جسيمات النحاس النانوية فعالية تثبيطية عالية مقارنة بالمضادات الحيوية والمتمثلة بقطر تثبيط 30.1 ملم عند تركيز 0.2 ملغم /مل، 28.1 ملم عند تركيز 0.1 ملغم / مل ،33.2 ملم عند تركيز 0.025 ملغم / مل. اما التركيز المثبط الادنى لبكتريا Escherichia coli كان عند تركيز 0.050 ملغم / مل بقطر تثبيبطي 25.2 ملم وبتركيز 0.075 ملغم / مل بقطر تثبيطي 26.1 ملم .تبين ان زيادة التثبيط تزداد عند التراكيز المنخفضة والعالية لجسيمات النحاس النانوية . وقد تبين ان جسيمات النحاس النانوية لها قدرة تثبيطية ممتازة ضد بكتريا E.coli المعزولة من المسالك البولية بالمقارنة مع المضادات الحيوية وهذا يأخذ امكانية الاستفادة من جسيمات النحاس النانوية كمادة مثبطة للاحياء المجهرية وكمواد مساندة للمضادات الحيوية ومعالجة التهاب المسالك البولية.
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